This blog provides information and resources for healthier living, wellness and a number of health topics including specific medical conditions. It is also a resource for conditions commonly considered to be environmental illnesses including CFS, FM, PTSD, obesity, diabetes, insulin resistance, MCS, heart disease, and a number of other conditions that are potentiated by contaminants in the air, soil and water including autism, sick building syndrome and sickness behavior just to name a few. This blog will try to focus on less scientific and more real-world news and application.



Monday, September 7, 2009

Loss of Nrf2 Signaling with ER Stress

Loss of Nrf2 Signaling with ER Stress: "We have explained that several factors can lead to impairment of Nrf2 including nutrition, actions of other proteins that interact with it, genetic factors, aging, endoplasmic reticulum stress, etc. On the other hand, ER stress is characterized by the accumulation of misfolded proteins, altered Ca2+ regulation and up-regulations of other proteins including GRP78. Consistent activation of TRPV1,"
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