This blog provides information and resources for healthier living, wellness and a number of health topics including specific medical conditions. It is also a resource for conditions commonly considered to be environmental illnesses including CFS, FM, PTSD, obesity, diabetes, insulin resistance, MCS, heart disease, and a number of other conditions that are potentiated by contaminants in the air, soil and water including autism, sick building syndrome and sickness behavior just to name a few. This blog will try to focus on less scientific and more real-world news and application.



Monday, September 28, 2009

Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion

Title: Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion.

Summary: "enhanced sensitivity of Nrf2 -/- vs. Nrf2 +/+ cells does not reflect basal differences in antioxidative capacity, but rather an impaired ability to mount an adaptive response to sustained oxidative stress.

Read more about Nrf2 in: HEIRS Blogs, HEIRS Library

Osburn, W. O., Wakabayashi, N., Misra, V., Nilles, T., Biswal, S., Trush, M. A., and Kensler, T. W. (2006). Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion. Archives of biochemistry and biophysics, 454(1):7-15. http://www.citeulike.org/group/7376/article/4023104
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