This blog provides information and resources for healthier living, wellness and a number of health topics including specific medical conditions. It is also a resource for conditions commonly considered to be environmental illnesses including CFS, FM, PTSD, obesity, diabetes, insulin resistance, MCS, heart disease, and a number of other conditions that are potentiated by contaminants in the air, soil and water including autism, sick building syndrome and sickness behavior just to name a few. This blog will try to focus on less scientific and more real-world news and application.



Sunday, September 6, 2009

TRPV1 and Endoplasmic Reticulum Stress

TRPV1 and Endoplasmic Reticulum Stress: "Activation of TRPV1 can cause endoplasmic reticulum stress which follows a pathway that leads to Nrf2 and unfolded protein response. Diabetes can lead to the unfolded protein response. In addition, chronic diabetic neuropathy can lead to nerve degeneration. DRG from diabetic rats show increased oxidative stress and cell injury. TRPV1 may be an early characteristic of diabetic sensory"
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