Two Pesticides Linked to Parkinson's Disease

"New research shows a link between use of two pesticides, rotenone and paraquat, and Parkinson's disease. An international research team has demonstrated that the people they studied who used either pesticide developed Parkinson's disease approximately 2.5 times more often than non-users."


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Parkinsonian Power Failure: Neuron Degeneration May Be Caused by a Cellular Energy System Breakdown: Scientific American

"mitochondrial dysfunction occurs early and for whatever reason mitochondrial biogenesis is either impaired or not stepping up to the demand of the neurons.'"

Read more: Parkinsonian Power Failure: Neuron Degeneration May Be Caused by a Cellular Energy System Breakdown: Scientific American:

Mitochondrial metabolism modulation: a new therape... [CNS Neurol Disord Drug Targets. 2010] - PubMed result

"Particularly a deficiency in the mitochondrial respiratory chain complex I and cristae disruption have been consistently described in PD. Moreover, the products of PD-familial genes, including alpha-synuclein, Parkin, PINK1, DJ-1, LRRK2 and HTR2A, were shown to localize to the mitochondria under certain conditions.It seems that PD has a mitochondrial component so events that would modulate normal mitochondrial functions may compromise neuronal survival. "

Mitochondrial metabolism modulation: a new therape... [CNS Neurol Disord Drug Targets. 2010] - PubMed result

Caring for a Loved One with Parkinson’s: Keep Them Active

Caring for a Loved One with Parkinson’s: Keep Them Active

Parkinson's Disease Makes It Harder to Figure Out How Other People Feel

Parkinson's Disease Makes It Harder to Figure Out How Other People Feel

Nrf2 regulates microglial dynamics and neuroinflam... [Glia. 2010] - PubMed result

Nrf2 regulates microglial dynamics and neuroinflam... [Glia. 2010] - PubMed result: "Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease"

PON1 Variant Associated w 2X Increase in Parkinson's from Organophosphate

CiteULike: Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease.: "Manthripragada, A. D., Costello, S., Cockburn, M. G., Bronstein, J. M., and Ritz, B. (2010). Paraoxonase 1, agricultural organophosphate exposure, and parkinson disease. Epidemiology (Cambridge, Mass.), 21(1):87-94."

Researchers Firm-Up Evidence For Role Of Mitochondria In Parkinson's Disease

Researchers Firm-Up Evidence For Role Of Mitochondria In Parkinson's Disease

On-the-Job Pesticide Exposure Associated With Parkinson�s Disease

On-the-Job Pesticide Exposure Associated With Parkinson�s Disease

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease: "URL: Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease"