HEIRS Health, Wellness, Disease and Hints for Better Living!: TRPV1

This blog provides information and resources for healthier living, wellness and a number of health topics including specific medical conditions. It is also a resource for conditions commonly considered to be environmental illnesses including CFS, FM, PTSD, obesity, diabetes, insulin resistance, MCS, heart disease, and a number of other conditions that are potentiated by contaminants in the air, soil and water including autism, sick building syndrome and sickness behavior just to name a few. This blog will try to focus on less scientific and more real-world news and application.

Showing posts with label TRPV1. Show all posts

Sunday, September 6, 2009

H2S and Irritable Bowel Syndrome

H2S and Irritable Bowel Syndrome: "This just published study has indentified the upregulation of CBS and H2S from colonic bacteria as important signallers in visceral hypersensitivity associated with irritable bowel syndrome in a rat model. CBS plays an important role in the removal of homocysteine and synthesis of cysteine, a precursor of glutathione. DRG CBS-producing neurons are positive for TRPV1 and P2X3R establishing a role"

TRPV1 and Endoplasmic Reticulum Stress

TRPV1 and Endoplasmic Reticulum Stress: "Activation of TRPV1 can cause endoplasmic reticulum stress which follows a pathway that leads to Nrf2 and unfolded protein response. Diabetes can lead to the unfolded protein response. In addition, chronic diabetic neuropathy can lead to nerve degeneration. DRG from diabetic rats show increased oxidative stress and cell injury. TRPV1 may be an early characteristic of diabetic sensory"